holmesianscholar:

love-in-mind-palace:

anigrrrl2:

skulls-and-tea:

Friendly reminder that when Sherlock wrote this: 

image

he was days away from this: 

image

Beautifully put.

There is no platonic reading for this that holds water. Friends don’t fall apart from grief when their friend gets married. He was mourning the loss of his love. 

“I get a wife out of it, Jones gets the credit, pray what remains for you?”

“For me,” said Sherlock Holmes, “there still remains the cocaine-bottle.” And he stretched his long white hand up for it. 

hildyj:

I’m sure, like definitely sure, given the haphazard way the hobbit trilogy was put together that the whole “I lost my way twice” line was added at some point while filming on set when someone asked, “is there a reason for Thorin turning so much later than everybody else? I mean, besides giving him a more dignified and heroic entrance than the one in the book?” and everyone just looked at each other and went, “fuck it, let’s just say he couldn’t find the place” and went on their merry way

but like

the fandom has now turned it into a major character trait? entire fan fic plots hinge on the fact that Thorin couldn’t find his way out of an empty potato sack, several pieces of fan arts joke about it, and it’s become this beautifully humanizing part of this tragically doomed dwarf’s personality. And I just love that.

that’s what fan culture is to me: taking bits of the canon and expanding them and gluing them together in new and interesting ways.

and it’s all so beautiful

Cause of polycystic ovary syndrome discovered at last

scarletjedi:

sundaycrossing:

mindblowingscience:

The most common cause of female infertility – polycystic ovary syndrome – may be caused by a hormonal imbalance before birth. The finding has led to a cure in mice, and a drug trial is set to begin in women later this year.

Polycystic ovary syndrome affects up to one in five women worldwide, three-quarters of whom struggle to fall pregnant. The condition is typically characterised by high levels of testosterone, ovarian cysts, irregular menstrual cycles, and problems regulating sugar, but the causes have long been a mystery. “It’s by far the most common hormonal condition affecting women of reproductive age but it hasn’t received a lot of attention,” says Robert Norman at the University of Adelaide in Australia.

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Cause of polycystic ovary syndrome discovered at last